Monoclonal Antibody Infusion Therapy for COVID-19

If you have been diagnosed with COVID-19 and are at high risk for developing severe COVID-19, you may be eligible for monoclonal antibody treatment, which might prevent you from becoming sicker.

What Are Monoclonal Antibodies?

Antibodies are part of our natural defense against viruses such as SARS-CoV-2, the virus that causes COVID-19. But they take time for the body to make. Antibodies designed to attack COVID-19 have been developed, and in several studies have been shown to reduce the risk of progressing to severe COVID-19 and hospitalization when given early to people who test positive for COVID-19. This therapy is given as an infusion through an IV at one of the UNC Health infusion centers.

Are You High Risk for Severe COVID-19 and Eligible?

There are two situations in which you may be eligible to receive monoclonal antibodies:

You test positive for COVID-19


You live in a household with someone who received a positive COVID-19 test

  • Have mild symptoms for no more than 7 days
  • Are age 65+ OR Are less than 65 but have a chronic health problem that puts you at risk for severe COVID-19. These include obesity diabetes, lung disease, and heart disease, among others
  • Not experiencing any symptoms
  • Have not tested positive for COVID-19
  • Are age 12+
  • Are unvaccinated OR  are vaccinated and have a medical condition that can interfere with vaccine effectiveness


Monoclonal antibody therapy needs to be given as soon as possible after symptoms start to work—ideally within 4 days and no longer than 7 days.

Updated on February 17, 2022

The fastest way to see if treatment is available or if you are eligible is to call your primary care physician. 

UNC providers should check the intranet resources for treatment criteria and referral information (internal access link).

Where to Get Monoclonal Antibody Infusion Therapy

  • Children’s Specialty Clinic, Raleigh - Blue Ridge
  • UNC Rex Healthcare, Raleigh, NC
  • Caldwell Infusion Center, Lenoir, NC
  • Lenoir Hospital, Kinston, NC
  • Johnston Health, Smithfield, NC
  • Meadowmont Village, Chapel Hill
  • Nash COVID Infusion Unit, Rocky Mount, NC
  • Rockingham COVID Inpatient Unit, Eden, NC
  • Wayne Infusion Center, Goldsboro, NC
  • Pardee Hospital, Hendersonville, NC

Learn more about monoclonal antibodies with this fact sheet from the FDA.

If You Are Eligible

The fastest way to see if treatment is available or if you are eligible is to call your primary care physician.