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desvenlafaxine

Pronunciation: des VEN la FAX een

Brand: Khedezla, Pristiq

Pristiq

slide 1 of 16, Pristiq,

50 mg, square, pink, imprinted with W 50

Image of Pristiq
slide 1 of 16
    

Pristiq

slide 2 of 16, Pristiq,

100 mg, square, orange, imprinted with W 100

Image of Pristiq
slide 2 of 16
    

Desvenlafaxine

slide 3 of 16, Desvenlafaxine,

(as base) 50 mg, diamond, pink, imprinted with L189

Image of Desvenlafaxine
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Desvenlafaxine

slide 4 of 16, Desvenlafaxine,

(as base) 100 mg, diamond, brown, imprinted with L190

Image of Desvenlafaxine
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Desvenlafaxine

slide 5 of 16, Desvenlafaxine,

100 mg, round, pink, imprinted with M, DF 100

Image of Desvenlafaxine
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Desvenlafaxine Succinate

slide 6 of 16, Desvenlafaxine Succinate,

100 mg, square, orange, imprinted with WPI 3660

Image of Desvenlafaxine Succinate
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Desvenlafaxine Succinate

slide 7 of 16, Desvenlafaxine Succinate,

100 mg, round, brown, imprinted with L350

Image of Desvenlafaxine Succinate
slide 7 of 16
    

Desvenlafaxine Succinate

slide 8 of 16, Desvenlafaxine Succinate,

100 mg, square, red, imprinted with W 100

Image of Desvenlafaxine Succinate
slide 8 of 16
    

Pristiq

slide 9 of 16, Pristiq,

25 mg, square, tan, imprinted with W 25

Image of Pristiq
slide 9 of 16
    

Desvenlafaxine Succinate

slide 10 of 16, Desvenlafaxine Succinate,

25 mg, square, tan, imprinted with W 25

Image of Desvenlafaxine Succinate
slide 10 of 16
    

Desvenlafaxine Succinate

slide 11 of 16, Desvenlafaxine Succinate,

25 mg, round, beige, imprinted with 54 427

Image of Desvenlafaxine Succinate
slide 11 of 16
    

Desvenlafaxine

slide 12 of 16, Desvenlafaxine,

50 mg, round, pink, imprinted with M, DF 50

Image of Desvenlafaxine
slide 12 of 16
    

Desvenlafaxine Succinate

slide 13 of 16, Desvenlafaxine Succinate,

50 mg, square, pink, imprinted with WPI 3659

Image of Desvenlafaxine Succinate
slide 13 of 16
    

Desvenlafaxine Succinate

slide 14 of 16, Desvenlafaxine Succinate,

50 mg, round, pink, imprinted with L349

Image of Desvenlafaxine Succinate
slide 14 of 16
    

Desvenlafaxine Succinate

slide 15 of 16, Desvenlafaxine Succinate,

50 mg, square, pink, imprinted with W 50

Image of Desvenlafaxine Succinate
slide 15 of 16
    

Pristiq

slide 16 of 16, Pristiq,

50 mg, square, pink, imprinted with W 50

Image of Pristiq
slide 16 of 16
    

What is the most important information I should know about desvenlafaxine?

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Do not stop using desvenlafaxine without first talking to your doctor.

What is desvenlafaxine?

Desvenlafaxine is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant.

Desvenlafaxine is used to treat major depressive disorder.

Desvenlafaxine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking desvenlafaxine?

You should not use this medicine if you are allergic to desvenlafaxine or venlafaxine (Effexor).

Do not use desvenlafaxine within 7 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine. A dangerous drug interaction could occur.

Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with desvenlafaxine could cause a serious condition called serotonin syndrome.

Tell your doctor if you have ever had:

  • heart disease, high blood pressure, high cholesterol, or a stroke;
  • bipolar disorder (manic depression);
  • depression, suicidal thoughts;
  • liver or kidney disease;
  • glaucoma;
  • seizures or epilepsy;
  • lung or breathing problems;
  • a bleeding or blood clotting disorder; or
  • low levels of sodium in your blood.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Taking an SNRI antidepressant during late pregnancy could increase your risk of excessive bleeding after you give birth, and may cause serious medical complications in the baby. However, stopping the medicine may not be safe if you have a relapse of depression. Do not start or stop desvenlafaxine without asking your doctor.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of desvenlafaxine on the baby.

Ask a doctor if it is safe to breastfeed while using this medicine.

Not approved for use by anyone younger than 18 years old.

How should I take desvenlafaxine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take desvenlafaxine with water at the same time each day, with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Your blood pressure will need to be checked often.

Your symptoms may not improve for several weeks. You may have unpleasant symptoms if you stop using desvenlafaxine suddenly. Ask your doctor before stopping the medicine.

Part of a tablet shell may appear in your stool but this will not make the medicine less effective.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking desvenlafaxine?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, naproxen, Advil, Aleve, Motrin, and others. Using an NSAID with desvenlafaxine may cause you to bruise or bleed easily.

Avoid drinking alcohol.

What are the possible side effects of desvenlafaxine?

Get emergency medical help if you have signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

  • a seizure (convulsions);
  • easy bruising or bleeding (nosebleeds, bleeding gums), blood in your urine or stools, coughing up blood;
  • blurred vision, eye pain or swelling, or seeing halos around lights;
  • cough, chest discomfort, trouble breathing; or
  • low blood sodium --headache, confusion, problems with thinking or memory, weakness, feeling unsteady.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects may include:

  • dizziness, drowsiness, anxiety;
  • increased sweating;
  • nausea, decreased appetite, constipation;
  • sleep problems (insomnia); or
  • decreased sex drive, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect desvenlafaxine?

Using desvenlafaxine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Tell your doctor about all your other medicines, especially a blood thinner (warfarin, Coumadin, Jantoven) or other medicine used to prevents blood clots.

Other drugs may affect desvenlafaxine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your pharmacist can provide more information about desvenlafaxine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2021 Cerner Multum, Inc. Version: 12.02. Revision date: 6/17/2021.

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