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Hormone Inhibin A Test

Test Overview

The inhibin A test is done to measure the amount of this hormone in a pregnant woman's blood to see if the baby may have Down syndrome. Inhibin A is made by the placenta during pregnancy.

The level of inhibin A in the blood is used in a maternal serum quadruple screening test. Generally done between 15 and 22 weeks, this test checks the levels of four substances in a pregnant woman's blood. The quad screen checks alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), a type of estrogen (unconjugated estriol, or uE3), and the hormone inhibin A. The levels of these substances—along with a woman's age and other factors—help the doctor estimate the chance that the baby may have certain problems or birth defects.

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Why It Is Done

A test for inhibin A is done in addition to other tests to see if there is a chance of chromosome problems, such as Down syndrome.

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How To Prepare

In general, there's nothing you have to do before this test, unless your doctor tells you to.

How It Is Done

A health professional uses a needle to take a blood sample, usually from the arm.

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How It Feels

When a blood sample is taken, you may feel nothing at all from the needle. Or you might feel a quick sting or pinch.

Risks

There is very little chance of having a problem from this test. When a blood sample is taken, a small bruise may form at the site.

Results

A normal result means that the level of the hormone inhibin A is low, or negative. An abnormal result means the level of the hormone inhibin A is high, or positive.footnote 1 The level of the hormone must be reviewed with the quad screen blood tests.

All abnormal results will need to be discussed with your doctor.

References

Citations

  1. Pagana KD, Pagana TJ (2010). Mosby's Manual of Diagnostic and Laboratory Tests, 4th ed. St. Louis: Mosby Elsevier.

Credits

Current as of: June 16, 2021

Author: Healthwise Staff
Medical Review:
Sarah Marshall MD - Family Medicine
E. Gregory Thompson MD - Internal Medicine
Adam Husney MD - Family Medicine
Kathleen Romito MD - Family Medicine
Siobhan M. Dolan MD, MPH - Reproductive Genetics