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Home > Health Library > Crohn's Disease
Crohn's disease is a lifelong inflammatory bowel disease (IBD). In Crohn's disease, parts of the digestive system get swollen and have deep sores called ulcers. This can result in symptoms such as belly pain and diarrhea.
Crohn's disease can affect any part of the digestive tract (which goes from the mouth to the anus). Most common is Crohn's disease that affects the ileum (the part of the small intestine that joins the large intestine). But Crohn's disease can be in multiple places in the digestive tract at the same time.
This picture shows Crohn's disease that is affecting the ileum and parts of the large intestine (colon), including the rectum. This kind of disease pattern is called ileocolitis.
Doctors don't know what causes Crohn's disease. You may get it when the body's immune system has an abnormal response to normal bacteria in your intestine. Other kinds of bacteria and viruses may also play a role in causing the disease.
The main symptoms of Crohn's disease are belly pain and diarrhea (sometimes with blood). Some people may have diarrhea 10 to 20 times a day. Losing weight without trying is another common sign. You may have only mild symptoms or go for periods of time without symptoms. A few people have ongoing, severe symptoms.
Your doctor will ask you about your symptoms and do a physical exam. You may also have X-rays and lab tests to find out if you have Crohn's disease. You may have tests that look inside the colon, and you may have a biopsy.
The main treatment for Crohn's disease is medicine. Mild symptoms may be treated with nonprescription medicines to stop diarrhea. You may also use prescription medicines to treat and prevent symptoms. Your treatment will depend on your symptoms and how bad they are. Exercise, eat healthy meals, and don't smoke to help yourself feel better.
Crohn's disease can run in families. Your chances of getting it are higher if a close family member has it. People of Eastern European (Ashkenazi) Jewish background may have a higher chance of getting Crohn's disease. Smoking also puts you at a higher risk for the disease.
The main symptoms of Crohn's disease are belly pain and diarrhea (sometimes with blood). Some people may have diarrhea 10 to 20 times a day. Losing weight without trying is another common sign.
Less common symptoms include mouth sores, bowel blockages, anal tears (fissures), and openings (fistulas) between organs.
Infections, hormonal changes, smoking, medicines, and lifestyle changes can cause your symptoms to flare up. You may have only mild symptoms or go for long periods of time without any symptoms. A few people have ongoing, severe symptoms.
Crohn's disease is an ongoing (chronic) condition that may flare up throughout your life. It affects different people in different ways. Some people may have only mild symptoms. Others may have severe symptoms or problems caused by Crohn's that, in rare cases, may be life-threatening.
Things that may cause Crohn's disease symptoms to flare up include medicines, infections, hormonal changes, lifestyle changes, and smoking.
The disease can also go into remission. This means that it is not active and you have no symptoms.
Crohn's disease may cause sores, or ulcers, that tunnel through the intestine and into the nearby tissue. These are often around the anus and rectum. These tunnels, called fistulas, are a common problem with Crohn's disease. They may get infected. Crohn's disease can also cause anal fissures. These are narrow tears that extend from the muscles that control the anus (anal sphincters) up into the anal canal.
In long-term Crohn's disease, scar tissue may replace some of the inflamed or ulcerated intestines. This scar tissue can form blockages (bowel obstructions) or narrowed areas (strictures). These can prevent stool from passing through the intestines. Blockages in the intestines also can be caused by inflammation and swelling, which may improve with medicines. Sometimes blockages can only be treated with surgery.
Sometimes symptoms of Crohn's disease develop outside the digestive tract in other parts of the body. This can include in the eyes, liver, blood, and bones.
Call a doctor now if you have been diagnosed with Crohn's disease and you have one or more of the following:
If you have any of these symptoms and you have been diagnosed with Crohn's disease, your condition may have become much worse. Some of these symptoms also may be signs of toxic megacolon. This is a rare complication of Crohn's disease that requires emergency treatment. Without treatment, it can cause the colon to leak or rupture, which can be fatal.
People who have Crohn's disease usually know their normal pattern of symptoms. Call your doctor if there is a change in your usual symptoms or if:
Your doctor will ask you about your symptoms and do a physical exam. You may also have X-rays and lab tests to find out if you have Crohn's disease.
Tests that may be done to diagnose or evaluate Crohn's disease include:
Your treatment will depend on the type of symptoms you have and how bad they are.
Medicines are the most common treatment for Crohn's disease. Medicines can control or prevent inflammation in the intestines and help relieve symptoms. They also promote the healing of damaged tissues.
People who have more severe, long-lasting symptoms may need other treatments. These can include stronger or different medicines, surgery to remove part of the intestine, or a procedure called balloon dilation.
Medicines usually are the treatment of choice for Crohn's disease. They can control or prevent inflammation in the intestines. They help to:
Surgery for Crohn's disease may be done if:
When surgery for Crohn's is needed, it involves removing the diseased part of the intestine. As little of the intestine as possible is removed to keep the intestines working normally. The disease tends to return to other areas of the intestines after surgery.
Some people who have Crohn's disease need extra nutrition because severe disease prevents their small intestine from absorbing nutrients.
Liquid feedings may be done through a tube placed in the nose and down into the stomach or through a vein. Feedings may be needed when:
Supplemental feeding can restore good nutrition to children who are growing more slowly than normal. It also can build strength if you need surgery or have been weakened because of severe diarrhea and poor nutrition.
Supplemental feeding allows the intestines to rest and heal. But it's common for symptoms to return when you go back to a regular diet.
Current as of:
February 10, 2021
Author: Healthwise StaffMedical Review: E. Gregory Thompson MD - Internal MedicineAdam Husney MD - Family MedicineArvydas D. Vanagunas MD - Gastroenterology
Current as of: February 10, 2021
Author: Healthwise Staff
Medical Review:E. Gregory Thompson MD - Internal Medicine & Adam Husney MD - Family Medicine & Arvydas D. Vanagunas MD - Gastroenterology
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